Early Detection and Diagnosis

Know what to look for and when to ask questions

Early Detection and Diagnosis

Know what to look for and when to ask questions

Knowing what to look for—and knowing when to ask questions—can make a difference.

Parkinson’s disease can begin with subtle changes such as smaller handwriting, stiffness, a quieter voice, or slower movement. These changes may be mistaken for aging, stress, or another condition.

One symptom does not mean you have Parkinson’s. Talk with your healthcare provider if changes persist, progress, or are interfering with your activities of daily living. An early evaluation can help you get answers and connect with the right care.

Early Signs of Parkinson’s:

Symptoms vary by person and may involve movement or other body functions. Possible signs include:

These symptoms can have many causes, and experiencing one or more does not mean you have Parkinson’s disease. The important thing is to pay attention to changes that persist or continue and talk to your doctor about these concerns.

How Is Parkinson’s Diagnosed?

Parkinson’s is primarily diagnosed through a clinical evaluation of medical history, symptoms, and a neurological examination. No single test confirms Parkinson’s; blood tests, brain imaging, or other testing may be used to rule out other conditions or add information.

A New Tool to Support Diagnosis

The Syn-One Test®, developed by CND Life Sciences, uses three small skin biopsies to detect phosphorylated alpha-synuclein, a protein associated with Parkinson’s and other synucleinopathies. It can provide objective evidence to support a provider’s evaluation.

The Syn-One Test is not a stand-alone diagnosis and does not distinguish Parkinson’s from other synucleinopathies. Results must be considered with symptoms, history, and examination. CND Life Sciences states that it is a laboratory-developed test and is not FDA-cleared or approved. Ask your provider or a movement disorder specialist whether it is appropriate for you.

Learn more about the Syn-One Test:
CND Life Sciences – Syn-One Test

When to make an appointment: Contact your healthcare provider if you notice several changes, if a symptom continues or worsens, or if changes are affecting daily activities. Bring a list of symptoms, when they began, and all medications and supplements you take.

Who Should I See?

Start with your primary care provider, who can evaluate your symptoms and refer you to a neurologist. A movement disorder specialist is a neurologist with additional expertise in Parkinson’s and related conditions and may be especially helpful when Parkinson’s is suspected.

Before your appointment, write down:

If possible, bring someone with you. They may have noticed changes and can help you remember the discussion.

What Happens After a Diagnosis?

A Parkinson’s diagnosis can bring many emotions and questions, but it also provides a starting point for moving forward.

After a diagnosis, work with your healthcare team to understand treatment options, make exercise and healthy habits part of your routine, and connect with people who understand what you are experiencing.

You Don't Have to Navigate Parkinson's Alone

Whether you are concerned about symptoms, newly diagnosed, or supporting someone you love, you do not have to figure it out alone.

Reach out and join us today!

Let us help you navigate Parkinson’s with knowledge, community, and hope. Reach out today and take the next step forward—with us by your side!

Purse Bingo

An evening of dinner, dancing, prizes and commmunity support.

Pickleball 4 Parkinson's 2026

Help us help Hoosiers with Parkinson’s today!

Parkinson’s Exercise Videos

CLIMB Online

Our CLIMB Online YouTube Channel offers comprehensive, research-based exercise programs developed specifically for those with Parkinson’s. 

The CLIMB

The Indiana Parkinson Foundation is committed to giving people with Parkinson’s disease their lives back through active engagement in The CLIMB.
choose-to-move-race

2027 Choose to Move Race

 1 mile or 5K

Help us help Hoosiers with Parkinson’s today!